Hypha Discovery is a microbial technology company helping partners in pharmaceutical and agrochemical R&D succeed through the discovery and production of microbial and mammalian metabolites. We are experts in the scalable production of DMPK metabolites and generation of polar analogues, and are also a leading provider of unique natural product screening libraries and associated services.
NEWS & EVENTS
Come and meet us at the following events
9th-10th October, Excel Arena, London
Download a copy of our brochure on drug metabolites and C-H activated derivatives
Our brochure on drug metabolites and C-H activated derivatives is now available. Inside we feature interesting case studies and client projects, including the following topics:
- Phase l CYP and non-CYP metabolites
- Phase ll conjugated metabolites
- Isotopically labelled metabolites
- Lead diversification and late stage functionalization
- Polar / C-H activated derivatives
In our latest newsletter we look at superior drug derivatives via late stage hydroxylation. Biocatalytic late stage functionalization has become a useful tool in order to rapidly access and explore compounds with superior properties compared to the original drug candidate, either resulting in improved potency and/or increased metabolic stability.