Hypha’s Q1 2018 newsletter – Single-step synthesis of sequential drug metabolites

Single-step microbial production of sequential hydroxylated glucuronidated metabolites is the topic of our first scientific newsletter for 2018.

 

Many drugs and chemicals possess complex metabolism including those metabolized through both oxidative and conjugative routes. Our newsletter highlights two case studies where sequential oxidation and glucuronidation resulted in major human and mammalian metabolites that were required in mg-g scale for further testing. Read more in our newsletter here.