Hypha featured in Nature Reviews Drug Discovery paper on “Expanding the medicinal chemistry synthetic toolbox”

A 2018 Nature Reviews Drug Discovery paper by Bostrom et al on “Expanding the medicinal chemistry synthetic toolbox” features examples of the outputs of Hypha’s hydroxylation technology. Hydroxylation is a key tactic to consider as part of a late stage functionalization strategy where small changes can result in improved activity, selectivity, solubility and lipophilicity.

https://www.nature.com/articles/nrd.2018.116

A downloadable poster from the paper highlighting the importance of expanding the medicinal chemistry synthetic toolbox is available here.