The MycoDiverse™ Natural Products Library
MycoDiverse™ Screening Library - an extensive collection of low molecular weight chemo-diversity produced by Hypha’s stimulatory fermentation and available for discovery screening via collaboration.
Key features of the MycoDiverse™ Natural Products Library:
- Novelty: over 50% of discoveries from the collection are novel structure
- Low Molecular Weight: the chart below shows that the library is a source of lower molecular weight compounds than are usually found from other sources of natural products
- Assay compatibility: The library is proven to be compatible with phenotypic and biochemical target assays
Click here see a summary of the robust performance of our library in bioluminogenic HDAC enzyme activity assays, as published in the Journal of Biomolecular Screening (Epigenetic-Targeted Drug Discovery special issue)
The library, composed of 10,000 refined fractions from the fermentations of mushroom fungi, is supplied to our clients for bioassay. Active compounds are quickly purified and identified by Hypha and supplied to the client for further evaluation.
Our commercial terms present a low barrier to entry and reduced-risk progression as well as the guarantee of exclusive access to hit compounds.
"Hypha Discovery very efficiently purified and identified bioactive molecules from microbial extracts. The work was on behalf of major pharma and agchem companies, and Hypha certainly didn’t let us down."
Jean-Marc Seng MD, BIOtransfer