Microbial Natural Products

Microorganisms are renowned as a prolific source of natural products, many of which are medicinally important products. The enormous structural and chemical diversity of natural products is unmatched by any synthetic library of small molecules and natural products continue to inspire novel discoveries.

Hypha scientists are experts in the discovery, fermentation, purification and structure elucidation of microbial natural products and are able to support projects in any of these areas. Contact us if you have a project you think we may be able to help with.

Download the publication below from Marine Drugs 2017, 15(4), 84; doi:10.3390/md15040084 as an example of novel compounds produced at Hypha.

Establishing the Secondary Metabolite Profile of the Marine Fungus: Tolypocladium geodes sp. MF458 and Subsequent Optimisation of Bioactive Secondary Metabolite Production

 

Why work with us?

  • Our track record in natural products. Our client base of pharmaceutical and agrochemical multinationals and SMEs, is testament to our expertise in fermentation, purification, identification and biotransformation of small molecules.
  • Cost effective, flexible service. Clients may outsource entire programs or choose to work with us on a modular basis.  We can also troubleshoot and rework existing processes and provide a full handover to clients.
  • Our processes are scalable. Target molecules can be produced for further work from mg amounts to assess bioactivity, up to g scale and beyond for semi-synthetic modification.

Contact us to discuss how we can help your project succeed.

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