MetID Services Launch
September 19, 2025 1:25 pm Leave your thoughtsLaunch of New MetID Services Hypha Discovery is excited to announce that we have extended our metabolite identification services to...
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Author Archives for Julia Shanu-Wilson
Intestinal excretion of low metabolic clearance drugs
June 27, 2025 3:24 pm Leave your thoughtsPaper Pick – Intestinal Secretion Is a Potentially Important Clearance Mechanism for Low Metabolic Clearance Compounds In this paper, scientists...
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Biocatalytic paths to synthesis of Iptacopan metabolites
June 6, 2025 12:44 pm Leave your thoughtsBiocatalytic paths to the synthesis of selected metabolites of Iptacopan In a recent paper published in celebration of the 20th...
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Small but mighty: the impact of tertiary alcohols in drug design
May 7, 2025 6:33 pm Leave your thoughtsSmall but mighty: the impact of tertiary alcohols in drug design By Julia Shanu-Wilson Creating a drug with perfect drug-like...
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Q1 2025 – Launch of PolyUGTs Kits
March 13, 2025 10:02 am Leave your thoughtsLaunch of PolyUGTs Kits Our PolyUGTs screening and scale-up kits are now available! They’re a super easy way to make...
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Oxidative biotransformation of elinzanetant to 3 active metabolites
February 20, 2025 5:41 pm Leave your thoughtsOxidative biotransformation of elinzanetant to 3 active metabolites Elinzanetant is a dual neurokinin-1,3 receptor antagonist under development for treatment of...
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Welcome to Matt and Xianfu
February 20, 2025 9:02 am Leave your thoughtsWelcome to Matt and Xianfu We are delighted that Matthew Allen and Xianfu Li have joined Hypha’s team recently. Xianfu was previously at...
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Metabolism of the new pain drug Suzetrigine
February 7, 2025 3:35 pm Leave your thoughtsCYP3A-Mediated Metabolism of Suzetrigine By Julia Shanu-Wilson It’s been more than 20 years since a pain drug with a new...
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Metabolism of 2024 FDA Approved Small Molecules – PART 1
January 22, 2025 2:34 pm Leave your thoughtsMetabolism of 2024 FDA approved small molecules part 1 By Julia Shanu-Wilson Involvement of active metabolites The number of small...
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The Current State of Biotransformation Science 2024
December 12, 2024 5:34 pm Leave your thoughtsThe Current State of Biotransformation Science Industry Survey of In Vitro and In Vivo Practices, Clinical Translation, and Future Trends...
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