Q1 2026 – LC-MS/MS MetID Service
January 21, 2026 6:31 pm Leave your thoughtsQ1 2026 Newsletter – LC/MS-MS MetID Service Hypha provides a high quality LC-MS/MS based MetID Service to complement our existing...
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Author Archives for Julia Shanu-Wilson
Role of metabolites in drug-drug interactions
December 18, 2025 6:09 pm Leave your thoughtsPaper Pick – The role of metabolites in drug-drug interactions Our last paper pick of the year is an excellent...
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Metabolism of 2024 FDA Approved Small Molecules – PART 2
December 10, 2025 11:44 am Leave your thoughtsMetabolism of 2024 FDA Approved Small Molecules – PART 2 By Julia Shanu-Wilson As we near the end of 2025,...
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Prediction of Camizestrant human PK from integration of ADME studies and PK modeling data
November 12, 2025 12:32 pm Leave your thoughtsPaper Pick – The application of mechanistic absorption, distribution, metabolism and excretion studies and physiologically-based pharmacokinetic modeling in the discovery...
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Q4 2025 – MetID Services Launch
September 19, 2025 1:25 pm Leave your thoughtsLaunch of New MetID Services Hypha Discovery is excited to announce that we have extended our metabolite identification services to...
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Intestinal excretion of low metabolic clearance drugs
June 27, 2025 3:24 pm Leave your thoughtsPaper Pick – Intestinal Secretion Is a Potentially Important Clearance Mechanism for Low Metabolic Clearance Compounds In this paper, scientists...
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Biocatalytic paths to synthesis of Iptacopan metabolites
June 6, 2025 12:44 pm Leave your thoughtsBiocatalytic paths to the synthesis of selected metabolites of Iptacopan In a recent paper published in celebration of the 20th...
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Small but mighty: the impact of tertiary alcohols in drug design
May 7, 2025 6:33 pm Leave your thoughtsSmall but mighty: the impact of tertiary alcohols in drug design By Julia Shanu-Wilson Creating a drug with perfect drug-like...
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Q1 2025 – Launch of PolyUGTs Kits
March 13, 2025 10:02 am Leave your thoughtsLaunch of PolyUGTs Kits Our PolyUGTs screening and scale-up kits are now available! They’re a super easy way to make...
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Oxidative biotransformation of elinzanetant to 3 active metabolites
February 20, 2025 5:41 pm Leave your thoughtsOxidative biotransformation of elinzanetant to 3 active metabolites Elinzanetant is a dual neurokinin-1,3 receptor antagonist under development for treatment of...
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