A 2018 Nature Reviews Drug Discovery paper by Bostrom et al on “Expanding the medicinal chemistry synthetic toolbox” features examples… read more →

Zhou et al.  presented a poster at the 2018 ISSX Conference in Montreal on “Elimination of [14C]-LY3023414 by Aldehyde Oxidase… read more →

Hypha Discovery have issued a policy detailing our position on data protection in relation to the GDPR regulations that came… read more →

Biocatalytic optimisation of lead compounds by late stage functionalisation is becoming more widely applied within pharma companies to rapidly access… read more →

19th February 2018 We are pleased to announce that Hypha have moved from Uxbridge to larger facilities in Slough. The… read more →

Liam is attending the Drug Discovery Chemistry Lead Optimization for Drug Metabolism and Safety meeting on April 6th 2018 in… read more →

Single-step microbial production of sequential hydroxylated glucuronidated metabolites is the topic of our first scientific newsletter for 2018.   Many… read more →

Hypha’s newsletter for Q4 2017 focusses on the selective production of N-oxide metabolites, especially relevant where there is potential for… read more →

This quarter we look at interesting off-target activity of some drug metabolites, using the metabolism of valsartan to 4-hydroxyvaleryl-valsartan as… read more →

Scientists in the AgChem industry often need to access metabolites of pesticides and herbicides to meet regulatory requirements. For more… read more →