Rapid access to hydroxylated metabolites using PolyCYPs: client case study

Our latest PolyCYPs bulletin features a case study in which one of our US pharma clients needed rapid access to a hydroxylated drug metabolite. In this case study, Hypha undertook screening of the drug compound against a number of PolyCYPs isoforms to identify the best enzyme for scale-up of the specific hydroxylation reaction. Milligram amounts of the purified metabolite were supplied to the client along with a Certificate of Analysis within 3 weeks from receipt of the order.

Access a pdf of the client case study here.